REDOX Science

by Dr. Daniel Pompa

In a country with some of the most advanced science in the world, we also face some of the highest disease rates. The old paradigm of treating symptoms is no longer cutting it, and a population of natural health hunters is emerging. As new bodily mechanisms are being discovered and understood, our notion of healthcare is transforming as well. Concepts like redox are proving to be profound in addressing the root cause of illness and supporting health and longevity. Today we will explore redox science, and how you can use redox signaling molecules to transform your health for the better.

Modern Healthcare: It’s Time for Change

Our modern healthcare system is notorious for prescribing pharmaceutical medications to manage the symptoms of the disease. In doing so, we aren’t addressing the root cause. These drugs come with a host of side effects, which are then “treated” with more pharmaceuticals. This catch 22 can continue on indefinitely without ever truly healing the individual. Treating the root causes of a disease requires a much more profound understanding of our natural human biology.

One such discovery is that of redox, a signaling process that is involved with a wide range of biological processes from inflammation to cancer. By harnessing the wisdom of redox science, we can start to address the root causes of modern disease, and give the body the building blocks it needs to heal itself.

The Science behind Redox

What is redox? Redox refers to the loss or gain of electrons through reduction and oxidation. Redox signaling occurs when specific molecules like free radicals, reactive oxygen species, and other compounds influence the body and are like a warning sign that cells give one another. These signals allow cells to detect damage, protect themselves, and repair or replace injured cells.

Redox molecules are made by mitochondria using the solution that they themselves exist in– saline. Indeed, your cells contain saltwater, and your mitochondria use this sodium, chloride, hydrogen, and oxygen solution to generate redox signaling molecules. These highly reactive molecules then go to work or are converted back into salt water to be used again at a later date.

Redox Signaling Molecules and Cell Signaling

The body’s cells are like factories that generate fuel, or ATP, to power the body. ATP is created by the mitochondria within the cells, and these mitochondria are also responsible for intracellular communication. Cell signaling is vital for health because it ensures things like immune function, tissue repair, cell development, hormone operations, and essentially every single bodily process.

Inside the cell, mitochondria create these redox signaling molecules which enable communication between one another. Redox signals are like the language of cells, without them there would be no life as we know it. In fact, when our cells fail to communicate clearly with one another, autoimmune conditions become much more likely. Cells fail to distinguish between good and bad cells and the body accidentally begins to attack itself.

Redox Signaling Molecules and Age

These redox signaling molecules are made by the trillions daily by mitochondria inside of the cell, but these numbers start to drop significantly with age. This is due partially to the fact that our mitochondria lessen with age. They die off naturally, and this happens faster with trauma (injury) and due to toxicity. The irony here, of course, is that those with the least amount of mitochondria due to illness and toxicity, are the ones who need them most. We progressively have fewer mitochondria to make the redox signaling molecules. Therefore, the mitochondria that we do have work much less efficiently as we grow older.

On average, there is a 10% reduction in mitochondria and redox molecules per decade once someone has gone through puberty. This number is staggering and highlights the importance of optimizing redox potential as soon as possible. This reduction of redox signaling molecules impacts our bodies in many ways. One obvious example is the body’s ability to heal slows with age.

A bruise that may last a couple of days for a child might last a couple of weeks or months in an elderly person. Healing from the common flu as a teenager could last much longer, and become much more severe in an elderly person. Less redox signaling molecules = less communication between cells = longer periods to repair tissues and cells, and longer periods of immune recovery.

Higher Redox Potential, Better Health

Ultimately, the higher your redox potential, the healthier you will be. Redox potential is a strong indicator not only of health but also of longevity. This mechanism influences such a wide range of bodily functions. A high redox potential enables your body to heal damaged cells and create new ones, and it also plays a role in supporting your natural detoxification pathways as well as your immune function. Redox signaling molecules help your body to clear out toxins like heavy metals and BPA’s. Redox signaling also supports your immune system to fight off any exposure to pathogens, bacteria, and viruses. It’s the ultimate player for healing as well as preventative healthcare.

Good health is a balancing act between avoiding exposure to harmful elements while also being strong enough to overcome the exposures that we inevitably come in contact with. Even if you’re living in a pristine forest away from any modern pollution or toxins. Your body will require redox signaling molecules anytime you get injured or sick. As we age, these molecules become less available. Taking actions to boost your redox potential becomes especially important as you get older.

Being mindful of redox potential is an integral part of living a healthy lifestyle. Support your mitochondria at the cellular level by boosting its redox potential. This will magnify all the other efforts you make when it comes to a healthy diet, exercise, and rest. Give your body the building blocks to build these redox signaling molecules. Your mitochondria can continue to generate them, and support your health today and for years to come.

Boost Redox Potential with ASEA Red0x Supplement

Redox Signal Molecules are made inside your cells and are foundational to ALL cellular health. But your body begins to make less of these vital molecules as you are exposed to toxins, mental and physical stresses, and health challenges. In fact, even if we lived in a perfectly pristine, stress-free world, the simple act of aging past 20 decreases your body’s ability to make these molecules by approximately 10% every decade. Science said there was nothing you could do about it – until now! ASEA, sometimes called ASEA Water, is the ONLY supplement in the world to contain stabilized Redox Signaling Molecules. After almost two decades, millions of dollars of research and multiple patents, the scientists behindASEA achieved what the scientific community said was impossible!

Starting with nothing more than salt and water (similar to what is found inside your cells) and passing it through a complex three-day process, ASEA creates stabilized Redox Signaling Molecules outside of the body. There are only two places where you can find these vital molecules – inside every living organism and inside a bottle of ASEA.

References:

Adler, Victor, Zhimin Yin, Kenneth D. Tew, and Zeev Ronai. “Role of Redox Potential and Reactive Oxygen Species in Stress Signaling.” Oncogene18, no. 45 (1999): 6104-111. doi:10.1038/sj.onc.1203128.

Cheeseman, KH, and TF Slater. “An Introduction to Free Radical Biochemistry.” Oxford Academic 49, no. 3, 481-93. doi:10.1093/oxfordjournals.bmb.a072625.

Hancock, John, and Matthew Whiteman. “Cellular Redox Environment and Its Influence on Redox Signaling Molecules.” Reactive Oxygen Species, 2018. doi:10.20455/ros.2018.815.

Lobo, V., A. Patil, A. Phatak, and N. Chandra. “Free Radicals, Antioxidants and Functional Foods: Impact on Human Health.” Pharmacognosy Reviews4, no. 8 (2010): 118. doi:10.4103/0973-7847.70902.

What’s Your Reason?

The “Side Hustle” they call it. 
It seems everyone has one these days. Some do it just for fun while others do it to make ends meet.

Whatever your reason for wanting to put some extra dollars in the bank account each month, we invite you to give this a look. Watch the short video then click the link below it and follow the easy steps. 

Shoot us a note if you decide this side hustle is for you and we will be happy to show you the ropes.

Click Here to get the rest of the story.

Study Shows Signaling Pathways in Genes After Consuming Redox Supplement

The results of double-blind placebo based study on a Utah company’s Redox cell signaling supplement are in.

This initial study shows a unique Redox signaling supplement can signal human genes, which have “shut off” due to stress, toxins, age, etc., and turn them back on.

The company, ASEA Global, owns numerous patents on this new technology. They partnered with Taueret Laboratories, a leading genetic research laboratory, to conduct an observational study to understand how this Redox Signaling supplement affects the activation of human genes. The eight-week human study was reviewed and approved by Quorum Review Independent Review Board, ensuring the ethical integrity, safety, and control of the research study. The study was a randomized double-blind placebo controlled study.

60 participants were randomly placed into three groups, 25 in an active group (REDOX supplement), 25 in a placebo group (saline placebo), and 10 in a control group (did not drink either the REDOX supplement or the placebo). The placebo was derived from the same saline solution used to create the actual REDOX supplement for this study, but did not contain the company’s patented redox molecules.

Of the 60 participants, 41% were male and 59% were female, with the mean age 35.  Each participant, except for the control group, drank 4 ounces of REDOX supplement or placebo twice daily.

Participants had blood drawn at the beginning of the study and again at week eight of the study. Serum RNA was extracted using a PreAnalytix PAXgene Blood RNA Kit. Gene expression levels were then tested using Affymetrix PrimeView Array and differential expression within and between groups analyzed.

Results

Results of the eight-week study showed a 20 – 31% difference in gene expression abundance in five genes that are involved in pathway signaling, including regulatory network pathways. Long-term consumption of the REDOX supplement resulted in stable expression changes at the eight-week time point (figure 1). These genes are key in the health of the individual and play a vital role in five human health areas and dozens of pathways.

Pathway signaling genes are unique as they have the potential to influence a multitude of biological responses. Analysis of the five genes was provided through two pathway analysis programs, PANTHER (Protein ANalysis THrough Evolutionary Relationships) and WikiPathways. An example of a gene product that was expressed in this study that interacts with multiple important pathways is the EGR1 gene.

In order to better understand how the genes reacted post-study, the REDOX supplement group that saw the 20 – 31% change provided blood samples eight weeks post-study. The results demonstrated that all the changes seen while on the product had reverted back to their pre-study levels.

SUMMARY –

• The initial study data suggests that five genes expressed a change in transcript abundance.

• The REDOX supplement group saw gene activation results in regulatory pathway related genes that signal dozens of  important biological functions.

• The REDOX supplement and the placebo (saline) behaved differently.

• There were no harmful changes in the gene expression trends of the participants consuming either beverage during the course of the study. This is representative of long-term safety.

• Daily consumption of REDOX supplement over eight weeks  appears to result in stable expression changes.

• Changes in gene expression eight weeks post study in the REDOX supplement group were no longer observed. This suggests continued use of REDOX supplement is necessary to  sustain the observed gene expression results.

• Effects of consuming REDOX supplement are systemic.

• Effects are non-specific to race, sex or age, and were observed in all populations tested.

Redox Signaling Molecules in a Gel?

ASEA Global, located in Pleasant Grove, Utah, has spent the last decade cementing its brand as the leader in Redox Biochemistry based products. Their catch phrase “We are Redox” incapsulates that goal.

During it’s first 5 years it was a single product company with a Redox Signaling supplement said to contain redox signaling molecules. The product carries the company name ASEA and is a liquid saline-based solution which contains the afore mentioned molecules.

In 2014 the company announced a new topical gel for the skin using the same solution of redox signaling molecules and nano technology.

Branded RENU28, the gel formulation encourages the strength and resiliency of your skin’s cell reproduction in partnership with your body’s natural efforts to keep your skin healthy. The science behind RENU28 delivers gentle, effective treatment to repair and comfort aging or damaged skin. Through Redox Signaling technology, this unique gel provides essential support to the all-important cellular mechanisms that are the foundation of your skin’s structure. Vital to the health of living cells, RENU28 provides critical connections and communication between cells with Redox Signaling molecules to ensure optimum renewal and replenishment.

Dermatest, one of the leading dermatological research institutes in the world, gave RENU28 its coveted 5-star clinically tested seal. In clinical trials, twenty women used RENU28 for 28 days. In addition to standard dermatological tests, digital scans were made of individual features such as wrinkles and skin texture.

Redox Signaling Molecules are naturally created within every cell of the body. They are vital to your immune system and to the cellular healing mechanisms of your body. A proper supply of Redox Signaling Molecules enables cellular healing throughout your
body. As you age, your cells make fewer and fewer of these molecules and your body’s ability to combat everyday ailments and the effects of aging diminishes.

In order to keep the cellular mechanisms of your body performing properly, it is essential that you supplement and replenish these Redox Signaling Molecules. The only way that you can do that outside of your own cells, is through ASEA—the world’s only source for Redox Signaling Molecules.

Redox Signaling Made Easy (and Fun)

This simple video is an engaging and novel way to look at the power of Redox Signaling Molecules and how ASEA has captured this incredible science in a bottle.

Please share your comments, questions, or insights!

The Science Behind Redox Signaling Supplement

Prepared by: Gary Samuelson, Ph.D. Robertson D. Ward, M.D., FAAFP David Carpenter, N.D., C.Ac., C.C.I.

The North Carolina Research Campus, and the Appalachian State University Human Performance Laboratory, under the direction of Dr. David Nieman’s world renowned team of scientists, uncovered new findings proving that the consumption of ASEA empowers humans to shift the availability of free fatty acids. These calorie sources represent a more favorable and efficient source of fuel for exercise and all daily life activity.

Facts about Our Metabolism

Cells inside our body breathe! The processes of metabolism at a cellular level involves the consumption of molecular oxygen and large molecule energy sources (sugar, glycogen, fatty acids, and amino acids). Through the process of oxidative phosphorylation (cellular respiration…breathing!) the cells create energy (ATP). The mitochondria in our cells do this work, and this is where Redox Signaling molecules are created.

Metabolism and Athletes

We understand that our cells always strive to run at the greatest efficiency possible. Through the conditioning of our bodies, our cells learn to use certain fuel sources preferentially. We are all familiar with the fatigue and pain that happens after rigorously exercising out-of-shape muscle groups. This happens because the muscle exhausts the standard glycogen source for fuel and then shifts to anaerobic metabolism (using fuel without oxygen), which forms lactic acid metabolites. But trained distance runners have conditioned their bodies to utilize a different fuel source: fatty acids (which are 6 times more energy-providing than other sources). By using fatty acids, these athletes preserve their muscle glycogen stores for strenuous bursts, like at the end of races, and that means greater endurance.

This is important. Endurance athletes actually condition their bodies to use fatty acids as a preferred fuel source, sparing muscle glycogen and increasing endurance.

Specific Metabolite Research Findings with ASEA:

The astonishing results of this randomized, double-blinded, crossover, placebo-based research showed that after one week of drinking 4 ounces of ASEA daily, the test subjects demonstrated a shift in 43 of 108 metabolites measured from the blood sample. These shifts were revealed using ultra-sensitive mass-spectroscopic measurement techniques. These shifts were so great that it was thought that there might be a software anomaly and scientists requested a manual inspection to verify data.

The largest metabolite shifts were in serum fatty acids. Again, these shifts happened after one week of consumption and before any athletic activity. Fatty acids are typically mobilized from abdominal body fat stores. They included myristic acid, palmitic acid, oleic acid, stearic acid, palmitelaidic acid, and capric acid. Don’t let the “acid” part throw you off; these are sources of fuel for the human body.

The chemical markers of these fatty acids are called “metabolites,” and their various concentrations in our blood represent a fingerprint of our metabolic balance. The metabolite shifts found due to ASEA ingestion are profound and very beneficial to health, since these shifts mimic what the body does when seeking fuel efficiency; that is, using fatty acids as a preferred fuel source and sparing muscle glycogen.

These important metabolite changes have resulted in applications for new patents for ASEA, and have prompted further studies at the North Carolina Research Campus. Additionally, all of these changes occurred without any evidence of toxicity whatsoever on any basic organ functions in liver and kidney tissue.

Conclusions

These initial results from a larger study on athletic performance have demonstrated that ASEA, which is composed of Redox Signaling molecules, has a profound impact on mobilization of fatty acids as they aid with efficiency in cellular respiration. This favorable pattern of increased availability of fatty acids for fuel consumption represents a foundational shift in our metabolic fingerprint – a shift toward more effective patterns of fuel usage and energy output.

The Redox Signaling Supplement’s foundational technology is completely protected by U.S. patents 5,334,383;  5,507,932;  5,674,537;  5,731,008;  6,007,686;  6,117,285.

ASEA athletes are finding they can go farther, faster, longer without red-lining their heart rate or going into critical oxygen debt

• Redox Signaling molecules are the key to cell efficiency
• ASEA athletes increase cell efficiency, giving them a competitive advantage
• Clinical studies show 12% average increase in time to VT (ventilatory threshold)
• Tested athletes report shorter recovery time and less soreness and fatigue
• Clinically proven, 100% safe, completely free of banned substances

Redox Signaling Science – Metabolites

Research conducted by the renowned Human Performance Laboratory at Appalachian State University, validates what drinkers of the Redox Signaling supplement all around the world already know: It has profound positive benefits to the body. In fact, the research findings were so profound that even the scientists doing the research were astonished by the results.

We blogged about this research over a week ago, but for those of you who prefer to watch the movie rather than read the book, here’s a new video just released where those involved in the research tell the incredible story.

Clinical Trials Now Showing Advantages of Redox Signaling Supplement for Athletes

Study finds that after drinking ASEA for one week, athletes experienced shift in 43 metabolites

Salt Lake City, Utah — ASEA, LLC announces the release of groundbreaking findings at the Experimental Biology 2012 Conference in San Diego of a new study from the Human Performance Laboratory showing increased power output and endurance among competitive athletes.*

The study supervised by Dr. David C. Nieman, DrPH, FACSM at the Human Performance Laboratory, Appalachian State University, found that after drinking ASEA athletes experienced massive free-fatty acid mobilization in the blood PRIOR to exercise to a level normally found only after heavy exercise.

“These are very significant findings,” said Nieman. “Our research demonstrated that ASEA is causing mobilization of free-fatty acids PRIOR to exercise, making this source of fuel available at the outset of exercise or competitive performance. This has important implications, especially regarding glycogen sparing, which is something every athlete tries to achieve.”

Glycogen sparing is the use of non-carbohydrates as a source of energy during exercise so that the depletion of muscle glycogen is delayed. When glycogen is spared the body burns fats for energy, making a greater contribution to an athlete’s efforts during the initial stages of a race. This leaves more glycogen for the later stages of racing or exercise, and muscle fatigue will be delayed.

The research found that after drinking ASEA Redox Signaling Supplement for one week, athletes were experiencing a shift in 43 metabolites.

“We have rarely seen such a drastic difference. For 43 of those signals to change, that is a quarter of the metabolite profile that we are monitoring. It is a huge bump in metabolite shifts that are due to the ingestion of just one product,” said Nieman.

What do these metabolite shifts mean for athletes?

“Athletes actually started the exercise after drinking the Redox Signaling Supplement with a lot more of these free-fatty acids in their blood. The reason that is important is that the muscles will actually use that as fuel, sparing the muscle glycogen and the use of amino acids which is what we found as we analyzed the data,” said Nieman.

“Every understanding from the literature is that these probably came from the fat stores in the abdominal area,” said Nieman. “So if you drink the Redox Signaling Supplement we found that the fats go up in the blood. If you’re not exercising, those fats will still be used to support the body’s metabolism for life.”

Simply drinking ASEA for seven days mobilized fuel stores in the body from abdominal fat. For those that want to burn more fat during exercise the Redox Signaling Supplement is ideal. Even without exercise the freed up fat stores will be used by the body as fuel.

Although this is the first laboratory study of the Redox Signaling Supplement on athletes, many endurance athletes have been drinking the Redox Signaling Supplement and noticing improvements in their race times, recovery after racing/training, etc.

James Lawrence, World Record, Most Triathlons 70.3 races, said, “I’ve experienced all these tremendous benefits over the last few years when I’m doing all these world records, and maybe didn’t understand it, but was fearful to go off the product. With this new study it’s really helped me understand why I don’t get sore, and why I’m able to just lock in this strong pace and hold it for so long.”

Cody Waite, professional Xterra triathlete, had this to say about Dr. Nieman’s study. “My thoughts on the study are that I kind of already knew this through my own experience with the product. But at the same time it’s great to have that solid evidence that laboratory test make official. That gives it that official stamp of approval from the scientists and then the stamp of approval from lead athletes.”

Diana MacManus, three-time national swimming champion said, “With ASEA I’ve noticed that my times and my meets have improved significantly. Learning about the research behind ASEA boosts my confidence and reinforces what I already know.” Typically, muscle glycogen is reduced in the body during a single or many groups of energy expenditures. For example, during a single sprint muscle glycogen may deplete by 25% to 30% of the resting levels. Similarly, at the end of longer durations (60 to 90 minutes) of high, moderate and low exercise muscle, glycogen will be dramatically reduced or depleted.

The study included 20 fit athletes in a randomized, double-blind, placebo-based, cross-over study. After baseline testing for VO2Max and body composition, one-half of the athletes drank four ounces of ASEA each day for seven days. The other one-half of the athletes drank four ounces of a placebo for seven days. Then all athletes completed a 75-km cycling trial, with blood drawn prior to the trial, immediately after the trial and one hour after the trial.

After a “washout” period in which none of the athletes drank the Redox Signaling Supplement or the placebo, a seven day cross-over study was conducted. The original the Redox Signaling Supplement group drank the placebo and the original placebo group drank the Redox Signaling Supplement for a seven day period. Then all athletes completed a second 75-km cycling trial, with blood drawn prior to the trial, immediately after the trial and one hour after the trial.

The research demonstrated that drinking the Redox Signaling Supplement taps into the body’s largest energy reserves, freeing fatty acids from adipose tissue, BEFORE exercise or athletic competition.

“This unexpected mobilization of fatty acids in theory will lead to better endurance in athletes, assisting athletes to maintain a certain pace for longer periods of time,” said Nieman.

The research found that the release of fatty acids is coming from fatty adipose tissue, the body’s source of abundant, available energy. Adipose tissue is fat stored around the organs of the body, with the most common and largest fat store being the abdominal area. Adipose tissue triglycerides represent the largest energy reserve in the human body. Utilizing these stores is critical for prolonged endurance exercise.

The study also demonstrated that the athletes in the study experienced a massive increase in blood levels of ascorbic acid (vitamin C) after exercise. This could indicate less oxidative stress on muscles. Further research is being conducted to determine the implications of this increase.

“This study is the latest in ASEA’s commitment to ongoing research. The frontiers of redox signaling molecules and ASEA are constantly being pushed. This latest study is not a destination, but an on-ramp,” said Verdis Norton, Chief Executive Officer at ASEA.

Human Performance Laboratory

The mission of the ASU/NCRC Human Performance Laboratory is to investigate the influence of unique plant molecules (e.g, flavonoids such as quercetin, luteolin, and epigallocatechin 3-gallate or EGCG) on age-related loss of muscle mass (sarcopenia), muscle mitochondrial biogenesis, and exercise-induced changes in immune function, oxidative stress, and inflammation. The Human Performance Laboratory is located at Appalachian State University North Carolina Research Campus and is affiliated with the North Carolina Research Institute which brings together eight universities as well as researchers at Dole, General Foods and Monsanto.

The Company and Product

ASEA, LLC is a Salt Lake City-based company whose flagship product, also called ASEA, is the world’s first and only source of stable, balanced, native-to-the-body Redox Signaling molecules.

ASEA Redox Signaling Supplement is sold in a 32-ounce bottle and an eight-ounce flexible pouch made from environmentally friendly materials. The 32-ounce bottle is made from a durable plastic. The eight-ounce flexible pouch fits easily into a backpack, pocket or in athletic gear. Both packages were created from input from competitive athletes and everyday ASEA consumers. The eight-ounce pouch includes a one-way valve to keep the pouch contents clean and pure.

ASEA can be purchased through ASEA’s wide network of independent associates.

ASEA and Redox Signaling Molecules

ASEA, with its Redox Signaling technology, is a powerful new drink that helps both competitive and recreational athletes step up their game to new levels of performance.

ASEA is the original and only Redox Signaling product available today. It provides the body with two perfectly balanced sets of reactive molecules — the same molecules produced naturally by the mitochondria in every cell of the body. These vitally important molecules support the production of the ATP energy that fuels our cells, help activate antioxidants, minimize cellular damage, enhance cellular communication, and speed the healing response — all functions critical to athletic performance, endurance and recovery.

Redox Signaling is a burgeoning scientific field on a global scale with an impressive array of recent research advances. Only recently have ASEA scientists been able to produce stable mixtures of these Redox Signaling molecules outside living cells.

ASEA and its foundational technology is completely protected by U.S. patents  5,334,383;  5,507,932;  5,674,537;  5,731,008;  6,007,686; 6,117,285.

*These statements have not been evaluated by the Food and Drug Administration.  The product is not intended to diagnose, treat, cure or prevent any disease.  The North Carolina Research Institute and its members, including Appalachian State University, do not endorse any products.  The statements by NCRI scientists should not be construed as product promotion.

• http://www.adventurenetwork.com/2012/asea-cell-signaling-drink-may-enhance-athletic-performance/#.T5tU_6tDyBU
• http://www.runnersweb.com/running/news_2012/rw_news_20120425_ASEA.html

Redox Signaling Found Critical to Curbing Cell Suicide

Recent findings of researchers at the University of Vermont College of Medicine show that Redox Signaling molecules are crucial in the regulation of apoptosis.

The study findings, published in volume 16 issue 6 of the Journal of Antioxidants and Redox Signaling state, “Redox-based signaling governs a number of important pathways in tissue homeostasis. Among the biological processes regulated by redox signaling, apoptosis or programmed cell death is a highly conserved process important for tissue homeostasis.”

The study further stated, “Apoptosis can be triggered by a wide variety of stimuli, including death receptor ligands, environmental agents, and cytotoxic drugs. Recent discoveries demonstrate that redox-based changes are required for efficient activation of apoptosis. Among these redox changes, alterations in the abundant thiol, glutathione (GSH), and the oxidative post-translational modification, protein S-glutathionylation (PSSG) have come to the forefront as critical regulators of apoptosis.”

“This is an important finding to support the importance of Redox Signaling Molecules. Apoptosis, a foundational cellular mechanism, is preserved at all cost,” said Robertson Ward, M.D., FAAFP, member of the ASEA Science Advisory Council.

ASEA, LLC is a Salt Lake City-based company whose flagship product, also called ASEA, is the world’s first and only source of stable, balanced, native-to-the-body Redox Signaling molecules.

Redox Signaling Molecules are produced naturally by the mitochondria in every cell of our body. But as people age they produce less and less of these molecules, which are vitally important to activating antioxidants, promoting cellular health, and enhancing cellular communication.

ASEA is the only method to re-introduce Redox Signaling molecules into the human body. It is sold in a 32-ounce bottle and an eight-ounce flexible pouch made from environmentally friendly materials.

The product can be purchased through ASEA’s wide network of independent associates.

ASEA: FACT or FICTION

Guest Blog by Mike Bills
Posted by Permission

Since I have been doing this blog with my good friend Matt we often get asked a lot of questions regarding ASEA. A lot of the questions are from information seeking curious individuals that truly want to understand the message that we are trying to deliver. Other questions are from those trying to clear up misinformation and misunderstanding. Then still we have those that are extremely skeptical and think ASEA is a scam and they mean to trip us up. I do understand, I didn’t believe in ASEA until I saw it change lives with my own eyes. I have a very personal connection to this product.

I wanted to take a few moments and address some of the more common questions and also common misconceptions that I see when it comes to ASEA.

Fact or Fiction?: Redox Signaling was invented by ASEA to sell ASEA.

A: Fiction!

I wrote a blog article a while back titled “What is Redox Signaling” . In the article I encouraged individuals to Google Redox Signaling and determine for themselves the science. WOW! I was torn apart for not explaining it. My intention was that if you Google Redox Signaling you can find thousands of independent articles on Redox Signaling. This would show this emerging science of Redox Signaling is not concocted by ASEA. I wont make that mistake again. At the bottom of this article under Resources I will include several links to outside sources on Redox Signaling. In addition there are several books on Amazon dealing with the topic of Redox Signaling including Redox Biochemistry & a publication on Antioxidants & Redox Signaling.

Why spend so much time on Redox Signaling? The first step to understanding ASEA is to having a basic understanding in the Science Behind ASEA.

Fact or Fiction?: ASEA was created for a comp plan for a network marketing company.

A: Fiction!

I understand this question. A lot of network marketing companies are created by professional network marketers to be network marketing companies. They want to create a company so they develop a marketing plan and then go find the products to fill the comp plan. Their entire Differentiating Advantage is their comp plan. The product is an after thought.

If you watch the How ASEA was Founded Video or attend any Meet ASEA meetings where Verdis Norton and James Pack tell their story you will quickly learn that when Verdis and James acquired the technology behind ASEA the intention was to determine why it worked, then to sell the technology for a profit. In order to determine why ASEA was getting the results it was, Verdis found and enlisted the help of Atomic Medical Physicist Dr. Gary L. Samuelson. It was Dr. Samuelson that determined what ASEA was and why it was working. Once they had made this discovery they did intend to sell and had an offer from a pharmaceutical company. Dr. Samuelson begged Verdis not to sell the technology because it would “be lost to mankind” if he did. Verdis took Dr. Samuelson’s advice and later ASEA was born!

Fact or Fiction?: ASEA is protected by Patents

A: Fact

ASEA and its foundational technology are completely protected by U.S. patents 5,334,383; 5,507,932; 5,674,537; 5,731,008; 6,007,686; 6,117,285.

Click on the above patents and do your own due diligence!

Fact or Fiction?: ASEA is a formulation created in a lab and is synthetic.

A: ABSOLUTELY FICTION!

I would describe ASEA as a Discovery. Actually two major discoveries that are scientific breakthroughs.

First, ASEA has managed to create native to the body redox signaling molecules that are created by the mitochondria in each cell of your body – outside of the body!

Second, ASEA has stabilized these molecules in a bottle that allows you take drink or apply them topically to re-introduce them to the body. Your body sees them as Native!

To understand watch the ASEA Breakout Product Video

Fact or Fiction?: ASEA is a Scam

A: Most Definitely Fiction

I mentioned that at the beginning of this post I have a very personal connection to this product, let me explain. First, I am an independent ASEA associate, I am not an employee. I also do want to promote and sell ASEA for a profit. However it goes beyond that. I have personally seen great benefits to individuals both close to me and that I have met through this endeavor and I fell an obligation to share. There are those that have written many negative articles on ASEA on the internet and branding it as a scam. I will say that those individuals have not done their due diligence and have an agenda. In fact a couple of them we have reached out to, invited them to ASEA to find out for themselves, on our dime with no obligation just to see the truth. They have all declined.

I was first introduced to ASEA prior to the launch by members of my family. They had invested very large amounts of money and are shareholders of ASEA. They encouraged me to take a look at the product and the company as they had intimate knowledge being shareholders. They then connected me to the Daughter and the Son of the CEO Verdis Norton. Nancy Norton Thunell was the first distributor in ASEA, Member of the founders club, diamond founders club and is a Triple Diamond. I am happy to say she is my close friend and her and her brother Jon Norton work directly with me to share and promote this wonderful product.

I truly believe that if you share ASEA, you will make a significant substantial difference in the lives of someone that needs it. I have seen it over and over again.

Resources

Critical Care 10(208) (2006), “Reactive oxygen species: toxic molecules or spark of life?””, Shelden Magder (http://ccforum.com/content/10/1/208).

Biochemical Pharmacology 70 (2005) 811-823, “Redox regulation: A new challenge for pharmacology””, Daniel Frein, Stefan Schildknecht (http://www.ncbi.nlm.nih.gov/pubmed/15899473).

Redox signaling in biology and disease series intro, ““The expanding network of redox signaling: new observations, complexities and perspectives””, Roy J. Soberman (http://www.ncbi.nlm.nih.gov/pubmed/12618508).

J Radiat Res (Tokyo 2004) 45(3) 357-72 “Oxidative stress, radiation-adaptive responses, and aging””, Miura Y. (http://www.ncbi.nlm.nih.gov/pubmed/15613781).

Biochemistry (Moscow) 70(2) (2005), ““Mitochondrial Metabolism of Reactive Oxygen Species””, A Yu Andreyev (http://www.ncbi.nlm.nih.gov/pubmed/15807660).

Cardiovascular Research, v71, p247-258 (2006), “Redox Signaling in Hypertension”, Tamara M Paravicini (http://www.ncbi.nlm.nih.gov/pubmed/16765337).

Wound Rep Reg, v11 p431-438 (2003), “The general case for redox control of wound repair”, Chandan K. Sen (http://www.ncbi.nlm.nih.gov/pubmed/14617282).