Here are a number of questions commonly asked about Redox Signaling and ASEA, a new product containing balanced Redox Signaling Molecules. Dr. Gary L. Samuelson, Ph.D. Atomic Medical Physicist has provided answers to these questions.
What are the reactive Redox Signaling molecules in ASEA and how are they made?
There are over 15 independently-verified Redox Signaling molecules (formed from salt water) in ASEA, some of them are molecular complexes. In the literature, these Redox Signaling molecules are categorized into two species, Reactive Oxygen Species (ROS) and Reduced Species (RS). The stable Redox Signaling molecules and complexes in ASEA are made from salt water in a complex electrochemical catalytic process involving electromagnetic fields, fixed catalysts, frequencies, flows and temperatures, etc. This process is very similar to the physical processes that produce the native Redox Signaling molecules found inside living cells. A perfect redox-balance of both species is found in ASEA. The exact process and structure of the resulting molecules are not made public, however.
It is important to realize that this redox-balanced compound cannot be made by simply mixing together the isolated components. The foundational underlying production technology is essential. This manufacturing process produces compounds that have been scrutinized closely with over 15 years of comprehensive toxicity studies showing absolutely zero toxic response in every study and in every case. Even when placed in direct contact with very sensitive lung endothelial cells, ASEA induced no toxic response or inflammatory markers. This is surprising because scientists expected immediate and recognizable toxic response, but have found none in years of repeated testing.
How do the ASEA scientists translate safety experiments run on cell cultures to safety in humans, How do you know how much is safe for humans?
The technology behind ASEA is based on more than 15 years of comprehensive in vivo preclinical safety studies along with substantial efficacy feedback from several people who have been drinking these redox signaling compounds over many years. The recommended daily portion of 2 to 4 oz. per day for the average individual is based on these comprehensive studies and efficacies.
The experiments run on ultra-sensitive endothelial cell cultures, when placed in direct contact with ASEA, serve to confirm that the stable oral formulation in ASEA is manufactured correctly. The complete lack of toxic response (no inflammatory cytokines), even with extremely high concentrations of ASEA, indicates the expected characteristics of the correct formula. Human studies on common blood markers used to determine toxicity were also done, urine and genetic markers. All this contributes to a large body of conclusive evidence has been used to determine safety.
Does ASEA contain any additives, contaminants or nanoparticles?
No. It is pure and uncontaminated as necessary to maintain stability.
Have independent labs verified the existence of these Redox Signaling molecules in ASEA?
Yes. Independent labs have employed different methods, such as low temperature mass spectroscopy, electron spin resonance and several fluorescent spectrographic methods (UCLA, JEOL, PNNL, Ascentia, Active Spectrum) and have specifically identified several of the molecular components and complexes in ASEA. Some of these methods were developed to successfully detect some components of ASEA in the blood. An in-house, yet independent, laboratory has been set up near the production facility to run quality assurance on samples from every batch of ASEA and random-bottle samples. This laboratory employs fluorescent spectrographic methods that are commonly used on living cells to identify Redox Signaling molecules. All lab results so far have been consistent and conclusive.
How does ASEA activate and enhance antioxidants?
Antioxidants are activated and renewed inside living cells by reductive molecules that could be termed collectively as “reductants.” The redox-balanced mixture of molecules in ASEA contains an abundance of reductants. These reductants enable the antioxidants to neutralize oxidants. Laboratory results with living cells have demonstrated over a 500% increase in efficacy of two native master antioxidants, glutathione peroxidase (GPx) and superoxide dismutase (SOD) even when very small concentrations of ASEA were added.
This is not the end of the story, though. It was also shown in the same study that ASEA helps increase the rate of production of these native protective antioxidants in cells. Recall that ASEA demonstrated zero toxicity. Any mechanism of action that causes cells to produce more antioxidants almost always involves a response to some sort of low-level toxicity-induced oxidative stress. ASEA is able to elicit the production of antioxidants in cells without eliciting any toxic response or oxidative stress. The technology behind ASEA is the only mixture (able to do this), to date, that has been shown to elicit antioxidant production without eliciting a toxic response. In this sense, ASEA is very unique.
Do the Redox Signaling molecules in ASEA play any role in helping with radiation exposure?
The most dangerous aspect of radiation is that your DNA and the internal workings of your cells, especially in your critical glands and organs, are attacked by the free radicals and oxidative toxins kicked off by the elevated levels of radiation picked up from the surrounding atmosphere. The native antioxidants inside your cells, glutathione and SOD, protect the cells against such free radicals and oxidative damage. ASEA dramatically increases the efficiency and production of these native antioxidants, thereby helping your body effectively protect itself against such free radicals and oxidants. In addition to this, the Redox Signaling molecules in ASEA greatly enhance the body’s efforts to detect, repair, and replace the damaged cells that do result.